HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Akira Takeshita Selected Research

rho-Associated Kinases

3/2007Anti-ischemic effects of fasudil, a specific Rho-kinase inhibitor, in patients with stable effort angina.
9/2005Rho-kinase is an important therapeutic target in cardiovascular medicine.
5/2005Rho-kinase inhibitor improves increased vascular resistance and impaired vasodilation of the forearm in patients with heart failure.
1/2005Divergent effects of estrogen and nicotine on Rho-kinase expression in human coronary vascular smooth muscle cells.
10/2004[Inhibition of Rho-kinase by fasudil preventing anginal attacks associated with spastic angina: a case report].
10/2004Rho-kinase, a potential therapeutic target for the treatment of hypertension.
8/2004Inflammatory stimuli upregulate Rho-kinase in human coronary vascular smooth muscle cells.
5/2004Long-term inhibition of Rho-kinase suppresses left ventricular remodeling after myocardial infarction in mice.
5/2004Remnant lipoproteins from patients with sudden cardiac death enhance coronary vasospastic activity through upregulation of Rho-kinase.
2/2004Rho/Rho-kinase pathway in the brainstem contributes to hypertension caused by chronic nitric oxide synthase inhibition.
For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown:


Akira Takeshita Research Topics

Disease

26Heart Failure
01/2012 - 02/2002
19Inflammation (Inflammations)
11/2005 - 02/2002
15Myocardial Infarction
08/2005 - 01/2002
14Hypertension (High Blood Pressure)
04/2011 - 04/2002
11Neoplasms (Cancer)
08/2021 - 09/2006
10Fibrosis (Cirrhosis)
09/2005 - 02/2002
9Pituitary Neoplasms (Pituitary Adenoma)
08/2021 - 09/2007
9Myocardial Ischemia (Ischemic Heart Diseases)
03/2007 - 03/2002
9Arteriosclerosis
09/2005 - 02/2002
8Hypertrophy
12/2005 - 05/2002
7Stroke (Strokes)
01/2008 - 02/2002
6Acromegaly
08/2021 - 06/2007
6Death (Near-Death Experience)
01/2012 - 10/2009
6Coronary Artery Disease (Coronary Atherosclerosis)
10/2008 - 02/2002
6Coronary Vasospasm (Coronary Artery Vasospasm)
09/2005 - 04/2002
6Atherosclerosis
11/2004 - 11/2002
6Ventricular Remodeling
05/2004 - 02/2002
5Pituitary ACTH Hypersecretion
03/2022 - 10/2009
5Hyperplasia
09/2015 - 06/2002
5Infarction (Infarctions)
01/2008 - 02/2002
5Cardiomyopathies (Cardiomyopathy)
11/2005 - 05/2002
5Spasm (Spasms)
05/2004 - 02/2002
4ACTH-Secreting Pituitary Adenoma
03/2022 - 10/2009
4Adenoma (Adenomas)
01/2021 - 12/2015
4Insulin Resistance
11/2017 - 11/2002
4Diabetes Mellitus
07/2013 - 12/2003
4Cardiovascular Diseases (Cardiovascular Disease)
09/2006 - 04/2002
4Thrombosis (Thrombus)
09/2005 - 04/2002
4Atherosclerotic Plaque (Atheroma)
03/2004 - 04/2002
4Vascular Diseases (Vascular Disease)
03/2003 - 02/2002
3Left Ventricular Dysfunction
03/2010 - 07/2002
3Vascular Remodeling
09/2006 - 09/2003
3Chest Pain (Chest Pains)
10/2004 - 03/2002
3Coronary Stenosis (Coronary Artery Stenosis)
05/2004 - 01/2002
3Vascular System Injuries
03/2003 - 06/2002
2Thyroiditis
04/2021 - 11/2018
2Hyperthyroidism
11/2018 - 01/2015
2Growth Hormone-Secreting Pituitary Adenoma
05/2016 - 10/2010
2Cysts
04/2014 - 01/2013
2Anorexia Nervosa
01/2010 - 07/2005
2Acute Coronary Syndrome
10/2008 - 04/2002
2Breast Neoplasms (Breast Cancer)
06/2008 - 12/2006
2Parathyroid Neoplasms (Parathyroid Neoplasm)
01/2008 - 12/2005
2Microvascular Angina (Cardiac Syndrome X)
03/2007 - 01/2003

Drug/Important Bio-Agent (IBA)

19rho-Associated KinasesIBA
03/2007 - 02/2002
18Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
12/2004 - 02/2002
11Nitric Oxide (Nitrogen Monoxide)FDA Link
04/2011 - 02/2002
11Angiotensin IIIBA
09/2006 - 02/2002
11Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2006 - 05/2002
10CytokinesIBA
01/2006 - 05/2002
9fasudil (AT 877)IBA
03/2007 - 04/2002
7Transforming Growth Factor beta (TGF-beta)IBA
12/2004 - 03/2002
6NG-Nitroarginine Methyl Ester (L-NAME)IBA
10/2004 - 02/2002
5Glucose (Dextrose)FDA LinkGeneric
05/2016 - 12/2002
5Reactive Oxygen Species (Oxygen Radicals)IBA
04/2011 - 02/2003
5Nitric Oxide Synthase (NO Synthase)IBA
01/2008 - 09/2002
5Lactic Acid (Lactate)FDA LinkGeneric
03/2007 - 03/2002
5Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
09/2005 - 02/2002
5Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2004 - 03/2002
4Adrenocorticotropic Hormone (ACTH)FDA Link
08/2021 - 12/2015
4Transcription Factors (Transcription Factor)IBA
12/2015 - 09/2003
4Messenger RNA (mRNA)IBA
12/2015 - 07/2002
4Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
03/2010 - 04/2002
4Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA
09/2006 - 05/2002
4Monomeric GTP-Binding ProteinsIBA
10/2004 - 02/2002
3Insulin-Like Growth Factor I (IGF-1)IBA
08/2021 - 05/2016
3Pro-Opiomelanocortin (Proopiomelanocortin)IBA
01/2021 - 12/2015
3Bromodeoxyuridine (BrdU)IBA
01/2018 - 09/2003
3Insulin (Novolin)FDA Link
05/2016 - 09/2002
3Growth Hormone (Somatotropin)IBA
01/2015 - 10/2010
3Arginine (L-Arginine)FDA Link
12/2011 - 04/2002
3Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
03/2010 - 03/2002
3Biological ProductsIBA
01/2008 - 12/2004
3NF-kappa B (NF-kB)IBA
09/2005 - 08/2004
3hydroxyfasudilIBA
05/2004 - 02/2002
3ChemokinesIBA
05/2004 - 11/2002
3Chemotactic FactorsIBA
03/2003 - 11/2002
3Matrix Metalloproteinases (MMPs)IBA
02/2003 - 02/2002
2Hydrocortisone (Cortisol)FDA LinkGeneric
08/2021 - 01/2015
2Thyrotropin (Thyroid-Stimulating Hormone)FDA Link
04/2021 - 12/2014
2Thyroid HormonesIBA
04/2021 - 09/2006
2Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
04/2021 - 12/2014
2Ubiquitin-Specific ProteasesIBA
01/2021 - 02/2016
2LipidsIBA
11/2018 - 12/2004
2Temozolomide (Temodar)FDA LinkGeneric
02/2016 - 10/2009
2Hormones (Hormone)IBA
12/2015 - 12/2005
2Estrogen ReceptorsIBA
12/2015 - 06/2008
2Parathyroid Hormone (Parathormone)IBA
09/2015 - 12/2005
2Hemoglobins (Hemoglobin)IBA
01/2011 - 10/2009
2Angiotensin Receptor AntagonistsIBA
03/2010 - 03/2002
2Hypoglycemic Agents (Hypoglycemics)IBA
01/2010 - 09/2002
2DNA (Deoxyribonucleic Acid)IBA
10/2009 - 05/2004
2Atorvastatin (Lipitor)FDA Link
01/2008 - 02/2003
2C-Reactive ProteinIBA
12/2007 - 07/2003
2Peptide Hydrolases (Proteases)FDA Link
09/2007 - 11/2005

Therapy/Procedure

12Therapeutics
05/2022 - 09/2002
7Patient Readmission
01/2012 - 12/2006
5Percutaneous Coronary Intervention
10/2008 - 11/2002
5Stents
10/2004 - 04/2002
2Radiotherapy
03/2022 - 10/2009